Job opening at Rfam for a Senior Computer Biologist

March 1, 2010

We are very sorry to announce that Jennifer Daub will be leaving the Rfam group. She’s moving on to much greener, friendlier, sunnier and more picturesque pastures (New Zealand). Jen has been a tireless worker and has been a major asset for the group. She’ll be sorely missed.

However, this means that there is now an open spot in the group for another passionate member of the RNA community.

Are you excited by some of the cool new discoveries made in the RNA field on an almost daily basis? For example, the RNA switch recently found in a human mRNA [1], the cold responsive RNA thermosensor [2] and the host of ncRNAs
found in the bacterial metagenome [3]. What about the fascinating challenge of dealing with data from new technologies such as RNA-seq? For example, there have recently been screens that discovered ncRNAs in H. pylori [4], S. aureus [5],
H. sapiens [6], S. typhi [7], D. melanogaster [8] and L. monocytogenes [9]. Another challenge is how to incorporate the long ncRNAs such as the lncRNAs and friends [10]. If any of these discoveries interest you then perhaps we have the job for you.

Another important activity for our new Rfammer is interacting with the community of Wikipedians. All the annotations we write for our RNA families are added to Wikipedia [11]. They will also be involved in encouraging the community to contribute. Perhaps via our agreement with RNA Biology [12].

If you want to find out more, see the advertisement on the Sanger website.

[1] Ray et al. (2009) A stress-responsive RNA switch regulates VEGFA expression. Nature.
[2] Giuliodori et al. (2010) The cspA mRNA is a thermosensor that modulates translation of the cold-shock protein CspA. Molecular Cell.
[3] Weinberg et al. (2009) Exceptional structured noncoding RNAs revealed by bacterial metagenome analysis. Nature.
[4] Sharma et al. (2010) The primary transcriptome of the major human pathogen Helicobacter pylori. Nature.
[5] Abu-Qatouseh et al. (2010) Identification of differentially expressed small non-protein-coding RNAs in Staphylococcus aureus displaying both the normal and the small-colony variant phenotype. Journal of Molecular Medicine.
[6] Rederstorff et al. (2010) RNPomics: Defining the ncRNA transcriptome by cDNA library generation from ribonucleo-protein particles. Nucleic Acids Research.
[7] Perkins et al. (2009) A strand-specific RNA-Seq analysis of the transcriptome of the typhoid bacillus Salmonella typhi. PLOS Genetics.
[8] Jung et al. (2010) Identification of novel non-coding RNAs using profiles of short sequence reads from next generation sequencing data. BMC Genomics.
[9] Oliver et al. (2009) Deep RNA sequencing of L. monocytogenes reveals overlapping and extensive stationary phase and sigma B-dependent transcriptomes, including multiple highly transcribed noncoding RNAs. BMC Genomics.
[10] Guttman et al. (2009) Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature.
[11] Daub et al. (2008) The RNA WikiProject: community annotation of RNA families. RNA.
[12] Gardner and Bateman (2009) A home for RNA families at RNA Biology. RNA Biology.

Posted by Paul.

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One Response to “Job opening at Rfam for a Senior Computer Biologist”


  1. […] czar of Rfam in Cambridge UK, Paul Gardner, is advertising for a new co-czar. Jennifer Daub is off to New Zealand, which is great for Jen, but what will Rfam do without her? […]


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